AGTR1 (AT1) Antibody
BiCell Scientific
SKU:50401-50UL
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Protein Function
Plan your comparisons around AGTR1 (AT1) and use this antibody to analyze state-dependent differences. AGTR1 is a signaling node often evaluated by abundance, localization, and modification-dependent states. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol AT1.
Experimental Applications
Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Time course design can be decisive when regulation is transient or compartment dependent.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
- time-resolved changes following stimulation or inhibition
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
When interpreting AGTR1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Integrate the regular format version into your design so AGTR1 (AT1) signals can be interpreted alongside matched controls.
- Targets:
- AGTR1
- Research Area:
- Cardiovascular • Cell Signaling
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the N-terminal extracellular region of human AGTR1 receptor protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P30556
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C