AH7614

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Selleck Chemicals

S9477-5MG

€144,00 EUR
€144,00 EUR
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AH7614 is an antagonist of GPR used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cell signaling models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By blocking GPR, AH7614 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GPR
  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, AH7614 is appropriate when a defined chemical perturbant is needed to connect GPR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GPR
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cell Signaling
CAS No.:
6326-06-3
Molecular Weight:
351.42
Formula:
C₂₀H₁₇NO₃S
SMILES:
CC1=CC=C(C=C1)[S](=O)(=O)NC2C3=CC=CC=C3OC4=CC=CC=C24
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.