Alectinib (CH5424802)hydrochloride

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Selleck Chemicals

S5232-10MG

€144,00 EUR
€144,00 EUR
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Alectinib (CH5424802)hydrochloride is an inhibitor of ALK used in studies of MAPK / ERK Signaling. It is especially relevant in cancer and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.

By inhibiting ALK, Alectinib (CH5424802)hydrochloride can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ALK
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Alectinib (CH5424802)hydrochloride is appropriate when a defined chemical perturbant is needed to connect ALK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ALK
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
1256589-74-8
Molecular Weight:
519.08
Formula:
C₃₀H₃₄N₄O₂·HCl
SMILES:
CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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