Amantadine HCl
Selleck Chemicals
SKU:S2451-25MG
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Amantadine HCl is an agonist of Dopamine Receptors used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in infectious disease and neuroscience models.
By activating Dopamine Receptors, Amantadine HCl can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In infectious disease and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Dopamine Receptors
- Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
- Agonist-response and downstream signaling studies
- GPCR pharmacology, ligand-binding, and signaling assays
Overall, Amantadine HCl is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in infectious disease and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Dopamine Receptors
- Target Class:
- GPCR
- Pathways:
- GPCR Signaling • Neurotransmission
- Research Area:
- Infectious Disease • Neuroscience
- CAS No.:
- 665-66-7
- Molecular Weight:
- 187.7
- Formula:
- C₁₀H₁₇N·HCl
- SMILES:
- C1C2CC3CC1CC(C2)(C3)N.Cl
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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