Amcenestrant (SAR439859)

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Selleck Chemicals

S9609-5MG

€383,00 EUR
€383,00 EUR
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Amcenestrant (SAR439859) is an antagonist of Estrogen/Progesterone Receptors and Estrogen Receptor used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.

By blocking Estrogen/Progesterone Receptors and Estrogen Receptor, Amcenestrant (SAR439859) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen/Progesterone Receptors and Estrogen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Amcenestrant (SAR439859) is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors and Estrogen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen/Progesterone Receptors • Estrogen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology
CAS No.:
2114339-57-8
Molecular Weight:
554.48
Formula:
C₃₁H₃₀Cl₂FNO₃
SMILES:
C1CC2=C(C=CC(=C2)C(=O)O)C(=C(C1)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)OC5CCN(C5)CCCF
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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