Amenamevir
Selleck Chemicals
SKU:S5552-1MG
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Amenamevir is an inhibitor of DNA/RNA Synthesis used in studies of DNA Damage Response. It is especially relevant in cancer, dna damage / repair, and infectious disease models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.
By inhibiting DNA/RNA Synthesis, Amenamevir can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving DNA/RNA Synthesis
- Pathway perturbation studies connected to DNA Damage Response
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, Amenamevir is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- DNA/RNA Synthesis
- Target Class:
- Enzyme
- Pathways:
- DNA Damage Response
- Research Area:
- Cancer • DNA Damage / Repair • Infectious Disease
- CAS No.:
- 841301-32-4
- Molecular Weight:
- 482.55
- Formula:
- C₂₄H₂₆N₄O₅S
- SMILES:
- CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4
- InChIKey:
- MNHNIVNAFBSLLX-UHFFFAOYSA-N
- PubChem:
- 11397521
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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