Amprenavir (VX-478)

1 1

Selleck Chemicals

S1639-5MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Amprenavir (VX-478) is an inhibitor of HIV Protease and PXR used in studies of Viral Entry / Replication and Metabolic Signaling. In practice, this places the compound in experiments that measure host-pathogen interactions, entry mechanisms, and replication-associated responses and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology, infectious disease, and metabolism models.

By inhibiting HIV Protease and PXR, Amprenavir (VX-478) can be used to examine host-pathogen interactions, entry mechanisms, and replication-associated responses and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In endocrinology, infectious disease, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HIV Protease and PXR
  • Pathway perturbation studies connected to Viral Entry / Replication and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays

Overall, Amprenavir (VX-478) is appropriate when a defined chemical perturbant is needed to connect HIV Protease and PXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, infectious disease, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HIV Protease • PXR
Target Class:
Protease
Pathways:
Viral Entry / Replication • Metabolic Signaling
Research Area:
Endocrinology • Infectious Disease • Metabolism
CAS No.:
161814-49-9
Molecular Weight:
505.63
Formula:
C₂₅H₃₅N₃O₆S
SMILES:
CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)N
InChIKey:
YMARZQAQMVYCKC-OEMFJLHTSA-N
PubChem:
65016
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.