Angiotensin Converting Enzyme 1 Antibody
Selleck Chemicals
SKU:F2456-20UL
Couldn't load pickup availability

About the Target
Angiotensin Converting Enzyme 1 is a target of interest in many antibody-based workflows. Angiotensin-converting enzyme 1 (ACE1) is crucial in the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and cardiovascular health. ACE1 catalyzes the conversion of angiotensin I, an inactive peptide, into angiotensin II, a potent vasoconstrictor that raises blood pressure and promotes inflammation and thrombosis.
Reported cellular context includes cell membrane, cytoplasm, membrane, and secreted, which can matter when signal is compared across treatments or changing cell states. Following Angiotensin Converting Enzyme 1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.
Research Context
Angiotensin Converting Enzyme 1 is commonly interpreted in the context of immunology, cardiovascular, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasm, and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.
Consider these angles when interpreting target-level changes:
- apparent redistribution between cell membrane, cytoplasm, and membrane across matched conditions
- context differences tied to immune-cell state, activation, or lineage composition
- changes linked to vascular, contractile, or hemodynamic cell-state cues
- signal-dependent shifts after ligand, inhibitor, or growth-factor perturbation
Variant Considerations
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for Angiotensin Converting Enzyme 1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.
Standardize sampling time, control choice, and downstream analysis thresholds so apparent differences in Angiotensin Converting Enzyme 1 reflect biology rather than handling. When interpreting Angiotensin Converting Enzyme 1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.
For multi-run studies, a shared reference condition can keep Angiotensin Converting Enzyme 1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.
- Targets:
- Angiotensin Converting Enzyme 1
- Research Area:
- Cardiovascular • Cell Signaling • Immunology
- Application:
- ELISA • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Specificity:
- Angiotensin Converting Enzyme 1 Antibody [L2A17] recognizes endogenous levels of total angiotensin converting enzyme 1 protein.
- Host:
- Rabbit
- Clonality:
- Monoclonal
- Clone:
- L2A17
- UniProt:
- P12821
- Storage Buffer:
- PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.