Aquaporin-1 (AQP1) Antibody - FFPE Validated
BiCell Scientific
SKU:20101-FFPE-50UL
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Protein Function
This antibody enables you to explore Aquaporin-1 (AQP1) with a direct, biology-first readout. Aquaporin-1 is a channel or transporter associated with regulated flux across cellular membranes. Look for shifts in distribution that track with phenotype changes.
Monitoring Aquaporin-1 alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- patterns consistent with apical or basolateral sorting
Workflow Perspective
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
For challenging targets, pairing Aquaporin-1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for Aquaporin-1 so cross-sample contrasts stay meaningful.
Select the fixed-section version to keep Aquaporin-1 (AQP1) interpretation aligned with your workflow goals.
- Targets:
- AQP1
- Research Area:
- Metabolism
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of human Aquaporin-1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P29972
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C