Aquaporin-6 (AQP6) Antibody
BiCell Scientific
SKU:20106-50UL
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Protein Function
Plan your comparisons around Aquaporin-6 and use this antibody to characterize state-dependent differences. Aquaporin-6 is a channel or transporter associated with regulated flux across cellular membranes. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol AQP6.
Experimental Applications
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Time course design can be decisive when regulation is transient or compartment dependent.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
If your study spans multiple model systems, it can help to define a shared reference condition for Aquaporin-6 so cross-sample contrasts stay meaningful.
If your study spans multiple model systems, it can help to define a shared reference condition for Aquaporin-6 so cross-sample contrasts stay meaningful.
Integrate the regular format version into your design so Aquaporin-6 signals can be interpreted alongside matched controls.
- Targets:
- AQP6
- Research Area:
- Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of rat Aquaporin-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q13520
- Homology:
- Synthetic peptide sequence shows 83.3% homology to mouse sequence and 55.5% homology to human sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C