Aquaporin-7 (AQP7) Antibody
BiCell Scientific
SKU:20107-50UL
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Scientific Overview
This antibody is suited for researchers who want to examine Aquaporin-7 and relate it to cell-state biology. Aquaporin-7 is a membrane protein linked to solute movement and gradient maintenance. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol AQP7.
Research Relevance
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- patterns consistent with apical or basolateral sorting
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Aquaporin-7 patterns can be compared across experiments without guesswork.
When interpreting Aquaporin-7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
As you refine hypotheses around Aquaporin-7, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- AQP7
- Research Area:
- Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse Aquaporin-7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O14520
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 38.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C