Aquaporin-8 (AQP8) Antibody

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BiCell Scientific

SKU:20108-50UL

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Size
Blocking Peptide
Quantity
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About the Target

Build reproducible readouts by using this antibody to examine Aquaporin-8 (AQP8) across matched sample sets. Aquaporin-8 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Use matched handling so differences reflect biology rather than processing.

Monitoring Aquaporin-8 alongside context markers can improve interpretation when phenotypes are subtle.

Research Context

Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Consider these angles when interpreting target-level changes:

  • patterns consistent with apical or basolateral sorting
  • surface versus intracellular pool distribution
  • relative abundance across engineered constructs
  • stimulus-dependent trafficking and turnover

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.

For challenging targets, pairing Aquaporin-8 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Aquaporin-8 patterns can be compared across experiments without guesswork.

Pair this regular format format with stable controls to keep Aquaporin-8 (AQP8) measurements coherent over time.

Targets:
AQP8
Research Area:
Metabolism
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (18-aa) derived from the C-terminal region of mouse Aquaporin-8 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
O94778
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 83.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C