ARL13B (ARL2L1) HiRe Antibody

Scientific Overview

When you need to evaluate ARL13B with attention to cellular organization, this antibody provides a focused option. ARL13B is a ciliary or centrosomal protein connected to microtubule-based organization. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

In some datasets and protocols, it is referenced by the gene symbol ARL2L1.

Research Relevance

Ciliary proteins are frequently assessed in relation to cell-cycle stage, serum conditions, and differentiation cues. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

• co-occurrence with intraflagellar transport markers
• changes in cilia incidence or apparent length in perturbation studies
• signal enrichment at basal bodies versus cytoplasm

Application-Specific Context

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

For challenging targets, pairing ARL13B measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so ARL13B patterns can be compared across experiments without guesswork.

The regular format version supports deeper biological narratives around ARL13B without overcomplicating setup.