ARL13B (Human) (ARL2L1) HiRe (Rabbit) Antibody - FFPE Validated

Scientific Overview

This antibody enables you to assess ARL13B with a direct, biology-first readout. ARL13B is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol ARL2L1.

Research Relevance

Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.

When building a narrative around the target, it helps to track:

• cell-cycle linked differences in localization
• changes in cilia incidence or apparent length in perturbation studies
• co-occurrence with intraflagellar transport markers
• signal enrichment at basal bodies versus cytoplasm

Application-Specific Context

For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

When interpreting ARL13B, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

When interpreting ARL13B, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Choose the fixed-section option when you want ARL13B results aligned to your sample format.