Asenapine maleate

1 1

Selleck Chemicals

S1283-25MG

€144,00 EUR
€144,00 EUR
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Asenapine maleate is an antagonist of 5-HT Receptors and Histamine Receptors used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in inflammation and neuroscience models.

By blocking 5-HT Receptors and Histamine Receptors, Asenapine maleate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving 5-HT Receptors and Histamine Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Asenapine maleate is appropriate when a defined chemical perturbant is needed to connect 5-HT Receptors and Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
5-HT Receptors • Histamine Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Inflammation • Neuroscience
CAS No.:
85650-56-2
Molecular Weight:
401.84
Formula:
C₁₇H₁₆ClNO·C₄H₄O₄
SMILES:
CN1CC2C(C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24.C(=CC(=O)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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