Sodium Potassium ATPase Antibody

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Selleck Chemicals

SKU:F2192-20UL

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About the Target

Sodium Potassium ATPase is a target of interest in many antibody-based workflows. The sodium-potassium ATPase (Na⁺/K⁺-ATPase) is a vital enzyme that maintains the balance of sodium (Na⁺) and potassium (K⁺) ions across the plasma membrane by actively transporting three Na⁺ ions out of the cell and two K⁺ ions into the cell, utilizing energy from ATP hydrolysis. This process is crucial for maintaining cellular homeostasis, membrane potential, and the excitability of cells, particularly in neurons and muscle cells. Depending on the literature source, Sodium Potassium ATPase may also be discussed as Sodium Potassium ATPase and alpha 1 Sodium Potassium ATPase.

Reported cellular context includes cell membrane, cell projection, and membrane, which can matter when signal is compared across treatments or changing cell states. Following Sodium Potassium ATPase across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state. In practice, this target is often considered at the family or isoform-group level, so experimental interpretation benefits from matched controls and clear comparison logic.

Research Context

Sodium Potassium ATPase is commonly interpreted in the context of neuroscience and cardiovascular research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cell projection, and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.

Consider these angles when interpreting target-level changes:

  • apparent redistribution between cell membrane, cell projection, and membrane across matched conditions
  • compartment-specific patterns relevant to neuronal polarity, transport, or synaptic context
  • changes linked to vascular, contractile, or hemodynamic cell-state cues
  • co-patterning with orthogonal markers and control conditions that clarify pathway state

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for Sodium Potassium ATPase. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.

Standardize sampling time, control choice, and downstream analysis thresholds so apparent differences in Sodium Potassium ATPase reflect biology rather than handling. When interpreting Sodium Potassium ATPase, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.

For multi-run studies, a shared reference condition can keep Sodium Potassium ATPase trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.

Targets:
ATP1A1 • ATP1A2 • ATP1A3
Research Area:
Cardiovascular • Neuroscience
Application:
FCM • IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Specificity:
Sodium Potassium ATPase Antibody [F11L6] recognizes endogenous levels of total Sodium Potassium ATPase protein.
Host:
Rabbit
Clonality:
Monoclonal
Clone:
F11L6
UniProt:
P05023P05026Q13733
Storage Buffer:
PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.