Aurora Kinase Inhibitor III

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Selleck Chemicals

SKU:S2931-2MG

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Aurora Kinase Inhibitor III is an inhibitor of Aurora Kinases and BTK and related targets used in studies of MAPK / ERK Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses in cancer, cell cycle, and cell signaling models.

By inhibiting Aurora Kinases and BTK and related targets, Aurora Kinase Inhibitor III can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Aurora Kinases and BTK and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling and Immune Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Aurora Kinase Inhibitor III is appropriate when a defined chemical perturbant is needed to connect Aurora Kinases and BTK and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Aurora Kinases • BTK • SYK • AURKA
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • Immune Signaling • Cell Cycle Regulation
Research Area:
Cancer • Cell Cycle • Cell Signaling • Immunology
CAS No.:
879127-16-9
Molecular Weight:
413.40
Formula:
C₂₁H₁₈F₃N₅O
SMILES:
C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
InChIKey:
RDTDWGQDFJPTPD-UHFFFAOYSA-N
PubChem:
9549303
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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