AVPR2 Antibody - Western Blot Validated
BiCell Scientific
SKU:50303-WB-50UL
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Protein Function
Plan your comparisons around AVPR2 and use this antibody to characterize state-dependent differences. AVPR2 is a signaling node often evaluated by abundance, localization, and modification-dependent states. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
Tracking AVPR2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Time course design can be decisive when regulation is transient or compartment dependent.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
- condition-to-condition comparisons with matched controls
Workflow Perspective
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
When interpreting AVPR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the denaturing-format option to keep AVPR2 analysis aligned with planned contrasts and endpoints.
- Targets:
- AVPR2
- Research Area:
- Cardiovascular • Cell Signaling • Endocrinology
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal intracellular region of mouse AVPR2 receptor protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P30518
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 78.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C