AZD1208

1 1

Selleck Chemicals

S7104-10MG

€144,00 EUR
€144,00 EUR
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AZD1208 is an inhibitor of PIM used in studies of JAK-STAT Signaling and Cell Cycle Regulation and related signaling programs. It is especially relevant in apoptosis, autophagy, and cancer models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and checkpoint control, mitotic progression, and proliferation timing.

By inhibiting PIM, AZD1208 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PIM
  • Pathway perturbation studies connected to JAK-STAT Signaling and Cell Cycle Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, AZD1208 is appropriate when a defined chemical perturbant is needed to connect PIM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PIM
Target Class:
Kinase
Pathways:
JAK-STAT Signaling • Cell Cycle Regulation • Apoptosis
Research Area:
Apoptosis • Autophagy • Cancer • Cell Cycle
CAS No.:
1204144-28-4
Molecular Weight:
379.48
Formula:
C₂₁H₂₁N₃O₂S
SMILES:
C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N
InChIKey:
MCUJKPPARUPFJM-UHFFFAOYSA-N
PubChem:
58423153
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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