AZD1981

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Selleck Chemicals

S7263-5MG

€95,00 EUR
€95,00 EUR
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AZD1981 is an antagonist of GPR used in studies of GPCR Signaling. It is especially relevant in cell signaling and endocrinology models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics.

By blocking GPR, AZD1981 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cell signaling and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GPR
  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, AZD1981 is appropriate when a defined chemical perturbant is needed to connect GPR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GPR
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cell Signaling • Endocrinology
CAS No.:
802904-66-1
Molecular Weight:
388.87
Formula:
C₁₉H₁₇ClN₂O₃S
SMILES:
CC1=C(C2=C(C=CC=C2N1CC(=O)O)NC(=O)C)SC3=CC=C(C=C3)Cl
InChIKey:
JWYIGNODXSRKGP-UHFFFAOYSA-N
PubChem:
11292191
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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