AZD3264
Selleck Chemicals
SKU:S7851-5MG
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AZD3264 is an inhibitor of IKK used in studies of NF-kB Signaling and Immune Signaling. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.
By inhibiting IKK, AZD3264 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving IKK
- Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, AZD3264 is appropriate when a defined chemical perturbant is needed to connect IKK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- IKK
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- NF-kB Signaling • Immune Signaling
- Research Area:
- Immunology • Inflammation
- CAS No.:
- 1609281-86-8
- Molecular Weight:
- 441.5
- Formula:
- C₂₁H₂₃N₅O₄S
- SMILES:
- CC1=C(C(=NO1)C)C2=CC(=C(C=C2)C3=CC(=C(S3)NC(=O)N)C(=O)N)OC4CCNC4
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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