AZD7762

1 1

Selleck Chemicals

S1532-2MG

€144,00 EUR
€144,00 EUR
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AZD7762 is an inhibitor of CHK and CHK1 and related targets used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer, cell cycle, and cell signaling models.

By inhibiting CHK and CHK1 and related targets, AZD7762 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CHK and CHK1 and related targets
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, AZD7762 is appropriate when a defined chemical perturbant is needed to connect CHK and CHK1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CHK • CHK1 • CHK2
Target Class:
Kinase
Pathways:
DNA Damage Response
Research Area:
Cancer • Cell Cycle • Cell Signaling • DNA Damage / Repair
CAS No.:
860352-01-8
Molecular Weight:
362.42
Formula:
C₁₇H₁₉FN₄O₂S
SMILES:
C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
InChIKey:
IAYGCINLNONXHY-UHFFFAOYSA-N
PubChem:
11152667
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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