Bavdegalutamide (ARV-110)

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Selleck Chemicals

S6965-5MG

€195,00 EUR
€195,00 EUR
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Bavdegalutamide (ARV-110) is a modulator of Androgen Receptor used in studies of Protein Degradation / Proteasome and Hormone Signaling. In practice, this places the compound in experiments that measure ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and ligand-dependent transcriptional programs and endocrine regulation in cancer, endocrinology, and protein homeostasis models.

By modulating Androgen Receptor, Bavdegalutamide (ARV-110) can be used to examine ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, endocrinology, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Androgen Receptor
  • Pathway perturbation studies connected to Protein Degradation / Proteasome and Hormone Signaling
  • Context-dependent response profiling and mechanism comparison
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Bavdegalutamide (ARV-110) is appropriate when a defined chemical perturbant is needed to connect Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Androgen Receptor
Target Class:
Nuclear Receptor
Pathways:
Protein Degradation / Proteasome • Hormone Signaling
Research Area:
Cancer • Endocrinology • Protein Homeostasis
CAS No.:
2222112-77-6
Molecular Weight:
812.29
Formula:
C₄₁H₄₃ClFN₉O₆
SMILES:
FC1=CC2=C(C=C1N3CCN(CC3)CC4CCN(CC4)C5=NN=C(C=C5)C(=O)NC6CCC(CC6)OC7=CC=C(C#N)C(=C7)Cl)C(=O)N(C8CCC(=O)NC8=O)C2=O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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