BAY 87-2243
Selleck Chemicals
SKU:S7309-10MG
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BAY 87-2243 is an inhibitor of HIF used in studies of Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses in angiogenesis, cancer, and cell signaling models.
By inhibiting HIF, BAY 87-2243 can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving HIF
- Pathway perturbation studies connected to Oxidative Stress Response
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, BAY 87-2243 is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- HIF
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- Oxidative Stress Response
- Research Area:
- Angiogenesis • Cancer • Cell Signaling • Oxidative Stress
- CAS No.:
- 1227158-85-1
- Molecular Weight:
- 525.53
- Formula:
- C₂₆H₂₆F₃N₇O₂
- SMILES:
- CC1=CC(=NN1CC2=CC(=NC=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(C=C6)OC(F)(F)F
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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