BBS1 Antibody (N-Terminus) - FFPE Validated
BiCell Scientific
SKU:90201N-FFPE-50UL
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Scientific Overview
Use this antibody to assess BBS1 Antibody N-Terminus when mapping complex behavior and signaling context. BBS1 Antibody N-Terminus is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following BBS1 Antibody N-Terminus across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Disruption of intraflagellar transport or basal body function can produce distinct localization signatures. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- cell-cycle linked differences in localization
- signal enrichment at basal bodies versus cytoplasm
- changes in cilia incidence or apparent length in perturbation studies
Application-Specific Context
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
For challenging targets, pairing BBS1 Antibody N-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
The fixed-section option supports mechanistic reading of BBS1 Antibody N-Terminus when interactions and context are the focus.
- Targets:
- BBS1
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the N-terminal region of human BBS1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8NFJ9
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C