BC-LI-0186

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Selleck Chemicals

SKU:E0488-5MG

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BC-LI-0186 is an inhibitor of DNA/RNA Synthesis used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response. It is especially relevant in cancer, cell cycle, and dna damage / repair models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control.

By inhibiting DNA/RNA Synthesis, BC-LI-0186 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DNA/RNA Synthesis
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, BC-LI-0186 is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DNA/RNA Synthesis
Target Class:
Enzyme
Pathways:
PI3K-Akt-mTOR Signaling • DNA Damage Response
Research Area:
Cancer • Cell Cycle • DNA Damage / Repair
CAS No.:
695207-56-8
Molecular Weight:
429.53
Formula:
C₂₂H₂₇N₃O₄S
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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