BCL2 Antibody
BiCell Scientific
SKU:10250-50UL
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Scientific Overview
When you need to evaluate BCL2 with attention to cellular organization, this antibody provides a focused option. BCL2 is a molecular target often examined to connect phenotype changes with underlying protein regulation. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring BCL2 alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
In many projects, target-level measurements help link perturbations to downstream phenotypes. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- baseline versus stimulated condition comparisons
- cross-sample normalization strategies
- interpretation alongside orthogonal readouts
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for BCL2 so cross-sample contrasts stay meaningful.
When interpreting BCL2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format variant when your project demands BCL2 readouts that respect preparation constraints.
- Targets:
- BCL2
- Research Area:
- Apoptosis • Cancer • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal region of mouse BCL2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P10415
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C