Bemegride

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Selleck Chemicals

S4197-50MG

€95,00 EUR
€95,00 EUR
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Bemegride is an antagonist of GABA Receptors used in studies of Neurotransmission. In practice, this places the compound in experiments that measure synaptic signaling, receptor activity, and neuronal excitability in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By blocking GABA Receptors, Bemegride can be used to examine synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GABA Receptors
  • Pathway perturbation studies connected to Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • Phenotypic profiling in neuroscience models

Overall, Bemegride is appropriate when a defined chemical perturbant is needed to connect GABA Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GABA Receptors
Target Class:
Other
Pathways:
Neurotransmission
Research Area:
Neuroscience
CAS No.:
64-65-3
Molecular Weight:
155.19
Formula:
C₈H₁₃NO₂
SMILES:
CCC1(CC(=O)NC(=O)C1)C
InChIKey:
ORRZGUBHBVWWOP-UHFFFAOYSA-N
PubChem:
92269
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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