β-Estradiol 17-Acetate

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Selleck Chemicals

SKU:S5236-25MG

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β-Estradiol 17-Acetate is a ligand of Estrogen/Progesterone Receptors used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in endocrinology models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By engaging Estrogen/Progesterone Receptors, β-Estradiol 17-Acetate can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen/Progesterone Receptors
  • Pathway perturbation studies connected to Hormone Signaling
  • Ligand-binding and signaling assays
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, β-Estradiol 17-Acetate is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen/Progesterone Receptors
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology
CAS No.:
1743-60-8
Molecular Weight:
314.42
Formula:
C₂₀H₂₆O₃
SMILES:
CC(=O)OC1CCC2C1(CCC3C2CCC4=C3C=CC(=C4)O)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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