BI-78D3

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Selleck Chemicals

S8201-5MG

€144,00 EUR
€144,00 EUR
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BI-78D3 is an inhibitor of JNK used in studies of PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling. It is especially relevant in cancer, cell signaling, and inflammation models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.

By inhibiting JNK, BI-78D3 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving JNK
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, BI-78D3 is appropriate when a defined chemical perturbant is needed to connect JNK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
JNK
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling • Inflammation
CAS No.:
883065-90-5
Molecular Weight:
379.37
Formula:
C₁₃H₉N₅O₅S₂
SMILES:
C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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