BIA

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Selleck Chemicals

SKU:E0945-5MG

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BIA is an antagonist of Calcium Channels and AKT used in studies of PI3K-Akt-mTOR Signaling and Calcium Signaling. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and calcium flux, excitability, and secretion-linked signaling in cancer, cardiovascular, and cell signaling models.

By blocking Calcium Channels and AKT, BIA can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cancer, cardiovascular, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Calcium Channels and AKT
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, BIA is appropriate when a defined chemical perturbant is needed to connect Calcium Channels and AKT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Calcium Channels • AKT
Target Class:
Ion Channel
Pathways:
PI3K-Akt-mTOR Signaling • Calcium Signaling
Research Area:
Cancer • Cardiovascular • Cell Signaling • Metabolism
CAS No.:
134271-74-2
Molecular Weight:
268.27
Formula:
C₁₅H₁₂N₂O₃
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.