BIP (HSPA5 or GRP78) Antibody
BiCell Scientific
SKU:54020-50UL
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About the Target
Use this antibody to evaluate BIP (HSPA5) when mapping complex behavior and signaling context. BIP is a target that supports characterization of cellular state through expression and localization readouts. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol HSPA5.
Research Context
In many projects, target-level measurements help link perturbations to downstream phenotypes. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- subcellular compartment mapping
- interpretation alongside orthogonal readouts
- cross-sample normalization strategies
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so BIP patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so BIP patterns can be compared across experiments without guesswork.
For challenging targets, pairing BIP measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format version to relate BIP (HSPA5) behavior to upstream cues and downstream consequences.
- Targets:
- HSPA5
- Research Area:
- Cancer • Cell Signaling • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal region of mouse BIP protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P11021
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 92.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C