Bisacodyl

1 1

Selleck Chemicals

S4047-50MG

€95,00 EUR
€95,00 EUR
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Bisacodyl is a substrate of COX-2 and TNF-alpha used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.

As a substrate linked to COX-2 and TNF-alpha, Bisacodyl can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving COX-2 and TNF-alpha
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling
  • Kinetic, turnover, and substrate-competition experiments
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Bisacodyl is appropriate when a defined chemical perturbant is needed to connect COX-2 and TNF-alpha with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
COX-2 • TNF-alpha
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
603-50-9
Molecular Weight:
361.39
Formula:
C₂₂H₁₉NO₄
SMILES:
CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
InChIKey:
KHOITXIGCFIULA-UHFFFAOYSA-N
PubChem:
2391
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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