BMS-687453

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Selleck Chemicals

S0170-5MG

€311,00 EUR
€311,00 EUR
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BMS-687453 is an agonist of PPAR and PPAR alpha used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By activating PPAR and PPAR alpha, BMS-687453 can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR and PPAR alpha
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, BMS-687453 is appropriate when a defined chemical perturbant is needed to connect PPAR and PPAR alpha with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR • PPAR alpha
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
1000998-59-3
Molecular Weight:
444.86
Formula:
C₂₂H₂₁ClN₂O₆
SMILES:
CC1=C(N=C(O1)C2=CC=C(C=C2)Cl)COC3=CC=CC(=C3)CN(CC(=O)O)C(=O)OC
InChIKey:
UJIBXDMNCMEJAY-UHFFFAOYSA-N
PubChem:
16725047
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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