BMS-813160

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Selleck Chemicals

S0085-5MG

€291,00 EUR
€291,00 EUR
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BMS-813160 is an antagonist of CCR used in studies of Immune Signaling and GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics in angiogenesis, cancer, and immunology models.

By blocking CCR, BMS-813160 can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CCR
  • Pathway perturbation studies connected to Immune Signaling and GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, BMS-813160 is appropriate when a defined chemical perturbant is needed to connect CCR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CCR
Target Class:
GPCR
Pathways:
Immune Signaling • GPCR Signaling
Research Area:
Angiogenesis • Cancer • Immunology • Inflammation
CAS No.:
1286279-29-5
Molecular Weight:
484.64
Formula:
C₂₅H₄₀N₈O₂
SMILES:
CC(=O)NC1CC(CCC1N2CCC(C2=O)NC3=NC=NC4=CC(=NN43)C(C)(C)C)NC(C)(C)C
InChIKey:
CMVHFGNTABZQJU-UHFFFAOYSA-N
PubChem:
51039119
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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