BMS-986260

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Selleck Chemicals

E6646-1MG

€194,00 EUR
€194,00 EUR
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BMS-986260 is an inhibitor of TGF-beta / Smad used in studies of TGF-beta / Smad Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to Smad-mediated transcription, differentiation, and fibrotic signaling in cancer, cell signaling, and developmental biology models.

By inhibiting TGF-beta / Smad, BMS-986260 can be used to examine Smad-mediated transcription, differentiation, and fibrotic signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TGF-beta / Smad
  • Pathway perturbation studies connected to TGF-beta / Smad Signaling
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, BMS-986260 is appropriate when a defined chemical perturbant is needed to connect TGF-beta / Smad with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TGF-beta / Smad
Target Class:
Signaling Pathway Modulator
Pathways:
TGF-beta / Smad Signaling
Research Area:
Cancer • Cell Signaling • Developmental Biology
CAS No.:
2001559-19-7
Molecular Weight:
382.78
Formula:
C₁₈H₁₂ClFN₆O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.