BO-264

1 1

Selleck Chemicals

S8965-5MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

BO-264 is an inhibitor of FGFR3 used in studies of MAPK / ERK Signaling and DNA Damage Response and related signaling programs. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control in apoptosis, cancer, and cell signaling models.

By inhibiting FGFR3, BO-264 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving FGFR3
  • Pathway perturbation studies connected to MAPK / ERK Signaling and DNA Damage Response and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, BO-264 is appropriate when a defined chemical perturbant is needed to connect FGFR3 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
FGFR3
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • DNA Damage Response • Apoptosis
Research Area:
Apoptosis • Cancer • Cell Signaling • DNA Damage / Repair
CAS No.:
2408648-20-2
Molecular Weight:
353.38
Formula:
C₁₈H₁₉N₅O₃
SMILES:
COC1=CC=C(C=C1)C2=NOC(=C2)NC3=NC(=NC=C3)N4CCOCC4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.