Bromfenac sodium hydrate

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Selleck Chemicals

SKU:S5786-25MG

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Bromfenac sodium hydrate is an inhibitor of COX and COX-1 and related targets used in studies of NF-kB Signaling and Immune Signaling. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.

By inhibiting COX and COX-1 and related targets, Bromfenac sodium hydrate can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving COX and COX-1 and related targets
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Bromfenac sodium hydrate is appropriate when a defined chemical perturbant is needed to connect COX and COX-1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
COX • COX-1 • COX-2
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
120638-55-3
Molecular Weight:
766.34
Formula:
C₃₀H₂₈Br₂N₂Na₂O₉
SMILES:
O.O.O.[Na+].[Na+].NC1=C(CC([O-])=O)C=CC=C1C(=O)C2=CC=C(Br)C=C2.NC3=C(CC([O-])=O)C=CC=C3C(=O)C4=CC=C(Br)C=C4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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