Broxyquinoline

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Selleck Chemicals

SKU:S4195-50MG

Regular price €144,00 EUR
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Broxyquinoline is a modulator of HIF used in studies of pathway modulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to pathway-dependent signal amplification or attenuation in cancer, cell signaling, and infectious disease models.

By modulating HIF, Broxyquinoline can be used to examine pathway-dependent signal amplification or attenuation. This target class is commonly examined through pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping. In cancer, cell signaling, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HIF
  • Context-dependent response profiling and mechanism comparison
  • Pathway-reporter and mechanistic-phenotyping studies
  • Phenotypic profiling in cancer, cell signaling, and infectious disease models

Overall, Broxyquinoline is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HIF
Target Class:
Signaling Pathway Modulator
Research Area:
Cancer • Cell Signaling • Infectious Disease
CAS No.:
521-74-4
Molecular Weight:
302.95
Formula:
C₉H₅Br₂NO
SMILES:
C1=CC2=C(C(=C(C=C2Br)Br)O)N=C1
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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