Bucladesine calcium

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Selleck Chemicals

E4793-50MG

€144,00 EUR
€144,00 EUR
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Bucladesine calcium is an activator of PKA used in studies of GPCR Signaling. It is especially relevant in cancer, cell signaling, and immunology models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics.

By activating PKA, Bucladesine calcium can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PKA
  • Pathway perturbation studies connected to GPCR Signaling
  • Gain-of-function pathway-activation studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Bucladesine calcium is appropriate when a defined chemical perturbant is needed to connect PKA with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PKA
Target Class:
Kinase
Pathways:
GPCR Signaling
Research Area:
Cancer • Cell Signaling • Immunology • Inflammation
CAS No.:
938448-87-4
Molecular Weight:
978.8
Formula:
C₁₈H₂₄N₅O₈P·½Ca
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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