BX-912

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Selleck Chemicals

S1275-2MG

€144,00 EUR
€144,00 EUR
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BX-912 is an inhibitor of PKA and CDK2 and related targets used in studies of PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer, cell cycle, and cell signaling models.

By inhibiting PKA and CDK2 and related targets, BX-912 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PKA and CDK2 and related targets
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, BX-912 is appropriate when a defined chemical perturbant is needed to connect PKA and CDK2 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PKA • CDK2 • CHK1 • c-Kit
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • MAPK / ERK Signaling • DNA Damage Response
Research Area:
Cancer • Cell Cycle • Cell Signaling • DNA Damage / Repair
CAS No.:
702674-56-4
Molecular Weight:
471.35
Formula:
C₂₀H₂₃BrN₈O
SMILES:
C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.