CACNA1A (Cav2.1) Antibody

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BiCell Scientific

SKU:11044-50UL

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Size
Blocking Peptide
Quantity
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About the Target

When you need to assess CACNA1A with attention to cellular organization, this antibody provides a focused option. CACNA1A is a channel or transporter associated with regulated flux across cellular membranes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Following CACNA1A across perturbations can help separate expression effects from compartment shifts.

Research Context

Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Consider these angles when interpreting target-level changes:

  • patterns consistent with apical or basolateral sorting
  • surface versus intracellular pool distribution
  • relative abundance across engineered constructs

Variant Considerations

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

For challenging targets, pairing CACNA1A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CACNA1A patterns can be compared across experiments without guesswork.

Use the regular format variant when your project demands CACNA1A readouts that respect preparation constraints.

Targets:
CACNA1A
Research Area:
Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (15-aa) derived from the N-terminal region of mouse Cav2.1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
O00555
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 86.7% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C