Cadherin-6 (CDH6) Antibody
BiCell Scientific
SKU:00106-50UL
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Biological Background
Designed to help you evaluate Cadherin-6 (CDH6), this antibody supports studies where protein context matters. Cadherin-6 is a structural regulator of intercellular boundaries and tissue architecture. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CDH6.
Use in the Laboratory
In cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.
Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.
To keep datasets interpretable, labs often document:
- co-localization patterns with cytoskeletal elements
- comparative profiling across cell states or perturbations
- subcellular redistribution at contact sites versus cytoplasm
Version Notes
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Cadherin-6 patterns can be compared across experiments without guesswork.
Use the regular format variant when your project demands Cadherin-6 (CDH6) readouts that respect preparation constraints.
- Targets:
- CDH6
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of mouse cadherin-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P55285
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C