Cadherin-6 (CDH6) Antibody - FFPE Validated

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BiCell Scientific

SKU:00106-FFPE-50UL

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Size
Blocking Peptide
Quantity
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About the Target

To connect mechanism with measurement, this antibody lets you evaluate Cadherin-6 in pathway-driven studies. Cadherin-6 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Monitoring Cadherin-6 alongside context markers can improve interpretation when phenotypes are subtle.

Research Context

Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.

Consider these angles when interpreting target-level changes:

  • co-localization patterns with cytoskeletal elements
  • comparative profiling across cell states or perturbations
  • changes in complex assembly with scaffold or adaptor proteins

Variant Considerations

Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for Cadherin-6 so cross-sample contrasts stay meaningful.

If your study spans multiple model systems, it can help to define a shared reference condition for Cadherin-6 so cross-sample contrasts stay meaningful.

Choose the fixed-section format to study Cadherin-6 in a way that stays anchored to pathway logic.

Targets:
CDH6
Research Area:
Developmental Biology
Application:
IHC-P
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the C-terminal region of mouse cadherin-6 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P55285
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C