Cadherin-6 (CDH6) (zebrafish) Antibody
BiCell Scientific
SKU:00106Z-50UL
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Scientific Overview
For consistent comparison across experiments, use this antibody to examine Cadherin-6 (CDH6) with a repeatable workflow. Cadherin-6 is a structural regulator of intercellular boundaries and tissue architecture. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol CDH6.
Research Relevance
Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- co-localization patterns with cytoskeletal elements
- comparative profiling across cell states or perturbations
- changes in complex assembly with scaffold or adaptor proteins
- subcellular redistribution at contact sites versus cytoplasm
Application-Specific Context
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
For challenging targets, pairing Cadherin-6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For multi-run studies, the regular format option helps keep Cadherin-6 (CDH6) trends comparable from experiment to experiment.
- Targets:
- CDH6
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Zebrafish
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal extracellular region of zebrafish cadherin-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q5WN09
- Homology:
- Synthetic peptide sequence showing 70.6% homology to human sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C