Cadherin-6 (CDH6) (zebrafish) Antibody - Western Blot Validated
BiCell Scientific
SKU:00106Z-WB-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you characterize Cadherin-6 in pathway-driven studies. Cadherin-6 is a membrane-associated component that helps organize cell-cell contacts and polarity. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following Cadherin-6 across perturbations can help separate expression effects from compartment shifts.
Research Context
Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- changes in complex assembly with scaffold or adaptor proteins
- comparative profiling across cell states or perturbations
- co-localization patterns with cytoskeletal elements
Variant Considerations
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Cadherin-6 so cross-sample contrasts stay meaningful.
For challenging targets, pairing Cadherin-6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the denaturing-format version to relate Cadherin-6 behavior to upstream cues and downstream consequences.
- Targets:
- CDH6
- Research Area:
- Developmental Biology
- Application:
- WB
- Reactivity:
- Zebrafish
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal extracellular region of zebrafish cadherin-6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q5WN09
- Homology:
- Synthetic peptide sequence showing 70.6% homology to human sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C