Calcitriol (1,25-Dihydroxyvitamin D3)

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Selleck Chemicals

S1466-1MG

€144,00 EUR
€144,00 EUR
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Calcitriol (1,25-Dihydroxyvitamin D3) is an agonist of Vitamin D Receptor used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in endocrinology and metabolism models.

By activating Vitamin D Receptor, Calcitriol (1,25-Dihydroxyvitamin D3) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Vitamin D Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Calcitriol (1,25-Dihydroxyvitamin D3) is appropriate when a defined chemical perturbant is needed to connect Vitamin D Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Vitamin D Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
32222-06-3
Molecular Weight:
416.64
Formula:
C₂₇H₄₄O₃
SMILES:
CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
InChIKey:
GMRQFYUYWCNGIN-NKMMMXOESA-N
PubChem:
5280453
Storage Temperature:
-80°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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