Calcium Dobesilate

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Selleck Chemicals

SKU:S4881-25MG

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Calcium Dobesilate is a research compound associated with p53 and BCL-2 and is relevant to studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.

The current annotation links Calcium Dobesilate to p53 and BCL-2, supporting target-focused studies that measure caspase-associated cell-death signaling and survival decisions without assigning a more specific primary mechanism than the dataset provides. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving p53 and BCL-2
  • Pathway perturbation studies connected to Apoptosis
  • Phenotypic profiling in apoptosis, cancer, and cell cycle models
  • Combination studies with orthogonal perturbagens

Overall, Calcium Dobesilate is appropriate when a defined chemical perturbant is needed to connect p53 and BCL-2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
p53 • BCL-2
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Cell Cycle
CAS No.:
20123-80-2
Molecular Weight:
209.2
Formula:
C₆H₅O₅S·½Ca
SMILES:
C1=CC(=C(C=C1O)S(=O)(=O)[O-])O.C1=CC(=C(C=C1O)S(=O)(=O)[O-])O.[Ca+2]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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