Calreticulin (CALR) Antibody
BiCell Scientific
SKU:54035-50UL
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Scientific Overview
Designed to help you explore Calreticulin, this antibody supports studies where protein context matters. Calreticulin is a cellular protein that can be tracked to understand expression patterns and compartmental behavior. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring Calreticulin alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
In many projects, target-level measurements help link perturbations to downstream phenotypes. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- interpretation alongside orthogonal readouts
- subcellular compartment mapping
- baseline versus stimulated condition comparisons
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for Calreticulin so cross-sample contrasts stay meaningful.
When interpreting Calreticulin, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The regular format version supports deeper biological narratives around Calreticulin without overcomplicating setup.
- Targets:
- CALR
- Research Area:
- Cell Signaling • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal region of mouse Calreticulin protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P27797
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 91.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C