Camizestrant (AZD9833)

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Selleck Chemicals

S8958-5MG

€517,00 EUR
€517,00 EUR
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Camizestrant (AZD9833) is an antagonist of Estrogen Receptor and Estrogen/Progesterone Receptors used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.

By blocking Estrogen Receptor and Estrogen/Progesterone Receptors, Camizestrant (AZD9833) can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen Receptor and Estrogen/Progesterone Receptors
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Camizestrant (AZD9833) is appropriate when a defined chemical perturbant is needed to connect Estrogen Receptor and Estrogen/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen Receptor • Estrogen/Progesterone Receptors
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology
CAS No.:
2222844-89-3
Molecular Weight:
476.51
Formula:
C₂₄H₂₈F₄N₆
SMILES:
CC1CC2=C(C=CC3=C2C=N[NH]3)C(N1CC(F)(F)F)C4=NC=C(NC5CN(CCCF)C5)C=C4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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